cardiocinetici Among the drugs, also known as cardio or cardenolidi, include some substances extracted from flowers, digital, common name for several plants of the genus Digitalis, the most important of which is Digitalis purpurea, Digitalis less important than the dawn and Digitalis lanata .
Family : Scrofulariaceae
Part used: leaves (Digitalis purpurea crowd FU)
Main components:
-cardiac glycosides: digitoxin, digitossigenina, gitalossigenina.
-digitanol-glycosides: digitalonina, digìnoside, digifolei
active derivatives are mainly two: the digoxin and digitoxin. The digitalis glycoside digitonin is another but has no effect on the heart and is mainly used for its power surfactant.
The mechanism of action must be taken into account the fact that these derivatives are cellular poisons: their pharmacological action comes from this, but of course this also leads to inherent dangers in the use of these substances. I have therefore digitalis high efficacy, but have a high toxicity and prolonged in time, which only recently was able to revert to the use of antidotes acting drugs, which opposes any action in the event of toxic overdose.
Massimo Capobianco
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